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This site is devoted to the quantitative description of gene regulation. It will store reviews of relevant internet resources (e.g. DNA-protein interaction databases, nucleosome positioning servers, and more items to come later), aggregated gene-regulation news (the right panel), the list of conferences and schools, as well as an overview of my own projects. You can contact me with any comments, suggestions and links or just post at the new forum.



Knowing the information about all molecular players and rules of their interaction, Nature "calculates" the transcription level for each gene. Is this biological game computable on a man-made computer? I take this as a working hypothesis. My current projects are aimed to develop a general methodology for the calculation of site- and context-specific multiprotein assembly on the DNA lattice and connect the mechanistic molecular logic of gene-regulation functions with the formal mathematics of systems biology in order to predict gene expression in chromatin. See the 
